Optimizing eCOA for Pain Management Clinical Trials—Your Selection Guide
Measuring pain in clinical trials presents unique challenges. Pain management clinical trials rely on subjective patient-reported outcomes, making data quality highly dependent on assessment design, participant usability, and consistent data capture across diverse populations.
Selecting the right eCOA for pain management clinical trials can significantly improve the accuracy, reliability, and usability of pain data. However, with a growing number of eCOA vendors and complex technical considerations, identifying a solution that truly supports pain research requires a structured, informed evaluation.
This practical eCOA selection playbook for pain management studies provides a clear framework to help sponsors and CROs assess technology options, align capabilities with protocol requirements, and avoid common implementation pitfalls that can impact timelines, data integrity, and patient experience.
Inside the eCOA for Pain Management Playbook

“Pain studies require a thoughtful approach to measurement and assessment selection. This playbook offers guidance research teams can use to evaluate eCOA options with their trial and patient population in mind. It is particularly useful when comparing technical specifications against the actual research requirements.”
— Karl McEvoy, PhD, VP, eCOA & Patient Technologies, YPrime
Beyond pain management, YPrime supports eCOA for clinical trials across GLP-1, oncology, immunology, CNS/neurology, dermatology, endocrinology, vaccines, and more. Explore our eCOA for clinical trials page and our eCOA for GLP-1 Playbook to learn more.