Everest Group Trailblazer in Patient Engagement
Patient Engagement in Clinical Trials
Participants don’t quit studies. They get lost in them.
Patient engagement in clinical trials decides who stays, what data you get, and when you finish. YPrime Patient Engagement lives inside YPrime eCOA, so participants know what’s next, sites chase less, and your endpoints hold.

Analyst recognized
A Trailblazer in Patient Engagement
Recognized for engagement that keeps participants in the study.
Everest Group named YPrime a Trailblazer in Clinical Trial Patient Engagement for building engagement directly into eCOA, with user-friendly design, personalization, and behavioral science behind it. A dedicated YPrime research team works directly with trial participants, and features such as the glucometer integration were developed with input from people living with diabetes.
Read the Trailblazer announcement
“YPrime’s clinical trial technology platform offers patient engagement features across eConsent and eCOA, leveraging user-friendly design, personalization, and behavioral science to drive patient retention and adherence.”
Patient Retention Is a Clinical Trial Priority
When participants disengage, studies lose more than people. They lose time, data quality, and the investment required to keep research moving.
Of clinical trial participants may drop out before their study is complete.1
Estimated cost associated with replacing a participant who leaves a clinical trial.1
Of clinical trials face delays in meeting enrollment timelines.1
of participants2
Participants don’t want more features. They want to understand.
YPrime’s research across more than 500 global participants and multiple user studies makes one thing clear: participants are not asking for more features. They are asking for clarity. 46% said a better explanation of why their participation matters.2
Read moreBuilt into eCOA
Engagement Built
into eCOA
Guidance sits in the same app where participants complete their assessments.
Many engagement tools sit outside the clinical workflow, adding platforms, logins, and channels to manage. YPrime puts patient engagement inside eCOA, so participants get the right guidance at the moment they complete their assessments.
Sponsors
Engagement without fragmented technology.
Sites
Clarity without adding to site workload.
Participants
Confidence from a clearer study experience.
Participant Hub
The YPrime eCOA
Participant Hub
The study explains itself, visit by visit.
At the center of the Participant Hub is the “For You” page. No searching emails, documents, or separate systems. Participants see what’s expected, when it’s due, and why it matters, right inside the eCOA app.
See the Participant HubStudy clarity
Protocol expectations and requirements explained in plain language.
Centralized study information
Visit schedules, study explanations, and resources in one governed place.
Task visibility
A clear view of upcoming assessments and priorities.
Protocol guidance
Training materials, FAQs, and approved documents on demand.
Continuous orientation
Participants stay aligned with study milestones between visits as well as at them.
Results
What Better Patient Engagement Does for Your Trial
Clearer studies produce more complete data and fewer dropouts.
Stronger adherence.
Participants stay on track with assessments and visits.
Protected endpoint integrity.
More complete, consistent data supports confident outcomes.
Less preventable dropout.
Lower burden keeps participants in the study.
Higher operational efficiency.
Fewer clarification requests and avoidable protocol deviations.
Fact sheet
Access our Patient Engagement Fact Sheet
The YPrime eCOA Participant Hub helps sponsors deliver clearer study experiences while strengthening adherence and protecting endpoint integrity.
What the “For You” page provides:
- Study Clarity – Participants understand protocol expectations, study requirements, and upcoming activities
- Centralized Study Information – Visit schedules, study explanations, and resources available in one governed location
- Task Visibility – A clear view of upcoming assessments, priorities, and study milestones
- Embedded Protocol Guidance – Training materials, FAQs, and approved documentation accessible directly within the eCOA experience
eCOA Participant Hub
See how the “For You” page gives every participant a clear next step, so fewer miss visits and more stay through the final one.
Get the Fact SheetPrefer to see it live? Book a personalized demo
eConsent + eCOA
Patient Engagement From First Consent to Final Visit
YPrime eConsent makes the study clear before day one. YPrime eCOA and the Participant Hub keep it clear through the last visit.
Let’s talk
Talk to a Patient
Engagement Expert
Bring us the study you’re worried will lose people.
We’ll show you how the Participant Hub fits your protocol and population.
Talk to a patient engagement expertInsights
Patient Engagement Insights
View all insightsIRT Masking Global Ophthalmology Study
Case Study: Faster IRT Startup in 45 Countries
Case Study: YPrime IRT in Action: Rapid COVID-19 Vaccine Study Implementation in Under 4 Weeks
Patient Engagement in Clinical Trials FAQs
What is patient engagement in clinical trials?
Patient engagement in clinical trials is the guidance, communication, and support that help participants understand a study, complete assessments on time, and stay through the final visit.
How can sponsors reduce patient dropout in clinical trials?
Make the study easier to understand. Clear visit guidance, task visibility, and on-demand protocol resources inside eCOA can help participants stay engaged.
What does patient dropout cost a clinical trial?
Replacing a participant who drops out can cost about $19,000. Dropout also creates gaps in endpoint data and can put study timelines at risk.
How does patient engagement improve clinical trial data quality?
Clear expectations help participants complete assessments on time and within compliance windows, supporting more complete and consistent endpoint data.
What is the YPrime eCOA Participant Hub?
It is a patient engagement experience built into YPrime eCOA. Its “For You” page shows what is expected, when it is due, and why it matters.
Do participants need a separate app for patient engagement?
No. YPrime patient engagement is built into eCOA, so participants use the same app for assessments and study guidance.
Does YPrime patient engagement support global clinical trials?
Yes. YPrime supports multilingual content and localized participant experiences across 100+ countries.
Sources
1 The True Cost of Patient Drop-outs in Clinical Trials
2 YPrime Engagement Survey Results (2022), survey of 500+ clinical trial participants
