Case Studies

Built-in Patient Engagement with IRT

  Built-in Patient Engagement with IRT Patient engagement remains a perennial topic in the ongoing discussion about improving patient retention in clinical trials. It sounds like an obvious choice, but to do it effectively and consistently across investigator sites requires systems that provide centralized communications, with mechanisms that allow blinded information exchange with patients. YPrime’s…

Details

Flexible Drug Dispensation at the Site Level

  Flexible Drug Dispensation at the Site Level YPrime’s configurable IRT system provides flexibility that is fundamentally different from what any other system can offer. When an emerging biopharmaceutical company approached YPrime for an IRT system for early phase oncology studies, they also needed a cost-effective solution as quickly as possible. The client was looking…

Details

Phase I IRT System Delivery in Days, not Weeks

  Phase I IRT System Delivery in Days, not Weeks Sometimes the biggest efficiency gains are not achieved through major innovations, but from practical applications of existing technology. What began as an IRT system to support a sponsor’s early phase study requirements ended up as an enterprise platform for all Phase I studies. Although Phase…

Details

Adaptive Randomization

  Adaptive Randomization When looking for a powerful and sophisticated IRT solution to support complex randomization, a pharmaceutical sponsor chose YPrime’s IRT+. The sponsor needed a custom solution to work across multiple protocols within the same program, involving approximately 3,000 patients with conjunctivitis. A major requirement specified the use of adaptive randomization instead of a…

Details

Configurable IRT: Unprecedented Flexibility and Speed without Shortcuts

  Configurable IRT: Unprecedented Flexibility and Speed without Shortcuts In early phase drug development, the need for speed is a given.  The sooner a sponsor can make a go/no go decision, the sooner they can prioritize promising compounds and fast track them for regulatory submission. A configurable IRT system can mean the difference between a…

Details

IRT Rescue Projects: What’s at Stake?

  Rescue projects and rush timelines are a fact of life in clinical trials. Yet, compressed timelines present risks of data loss or errors. YPrime recently managed a rescue situation involving an IRT system for a Phase II study within an emergency room setting. The project included development of a robust solution to support randomization…

Details