Clinical trial professional using YPrime eCOA platform on tablet, with platform interface shown on laptop and mobile device.

eCOA for Clinical Trials

eCOA for Clinical Trials
Built for Speed, Data Quality, and Global Execution.

Clinical trials demand accurate, timely, and patient-friendly data collection across regions, languages, and complex protocols. YPrime’s eCOA platform is purpose-built for clinical trials, helping sponsors and CROs accelerate study startup, improve data quality, and maintain inspection-ready oversight from first patient in through data lock.

YPrime eCOA (electronic Clinical Outcome Assessment) combines configurable workflows, advanced reporting, and patient-centered design to support global trials without compromising compliance or data integrity.

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eCOA Software for Clinical Trials for Speed, Flexibility, and Certainty.

YPrime’s configurable eCOA software adapts to protocol complexity, regional requirements, and mid-study change—without slowing trials down.

Faster Startup: Pre-validated eCOA platform reduces build, translation, and validation timelines
Global Scale: AI-powered eCOA localization supports 250+ languages and 100+ countries
Investigator Oversight: Enable investigators to review and sign off electronically for traceable, audit-ready compliance
Protocol Adaptability: Rapid updates for amendments without rework or disruption
Participant-Centered Design: Intuitive experiences drive compliance and reduce burden.

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Setting a New Standard in Clinical Trial Outcome Assessments.

97% say data
quality
is #1 factor

When choosing eCOA.2

90% say ease
of use
is #2 factor

When choosing eCOA.2

88% say faster
study startup
is #3 factor

When choosing eCOA.2

YPrime’s eCOA Portal 

—The New Standard.

YPrime redefines clinical trial efficiency with an eCOA portal that empowers sponsors and sites to quickly and seamlessly manage participant workflows, maintain visit schedules, and obtain full oversight of clinical trial progress.

Computer monitor displaying YPrime’s eCOA portal, showing participant workflow management, visit scheduling, and clinical trial progress tracking

Effortless management

Intuitive tools enable quick setup and streamlined participant tracking, optimizing the site user experience.

Flexible scheduling

Easily adapt visit schedules to support site staff and participants—improving trial efficiency.

Near real-time
insights

Access comprehensive trial data and dynamic reporting capabilities that enable informed decision-making and optimize trial outcomes through data-driven insights.

Schedule a Demo →

YPrime’s eCOA Portal 

—The New Standard.

YPrime redefines clinical trial efficiency with an eCOA portal that empowers sponsors and sites to quickly and seamlessly manage participant workflows, maintain visit schedules, and obtain full oversight of clinical trial progress.

Computer monitor displaying YPrime’s eCOA portal, showing participant workflow management, visit scheduling, and clinical trial progress tracking

Effortless management

Intuitive tools enable quick setup and streamlined participant tracking, optimizing the site user experience.

Flexible scheduling

Easily adapt visit schedules to support site staff and participants—improving trial efficiency.

Near real-time
insights

Access comprehensive trial data and dynamic reporting capabilities that enable informed decision-making and optimize trial outcomes through data-driven insights.

Schedule a Demo →

Configurable, Scalable eCOA for Complex Clinical Trial Protocols.

Every study is different. YPrime’s flexible eCOA platform adapts to your protocol, region, and patient population—without slowing you down.

Seamless management of diverse device strategies
Support for complex, long-duration, and high-enrollment studies
Full scalability across therapeutic areas, geographies, and study phases
Deep experience in CNS, metabolic disease, oncology, and rare indications

A Patient-Centered Approach Improves Compliance.

Better experiences lead to better data. YPrime’s eCOA app is designed using real-world usability research to support participants across age groups, regions, and therapeutic areas.

Clear Navigation: Step-by-step prompts and smart reminders
Device Flexibility: BYOD or provisioned devices
Connected Devices: Integrations with wearables, glucometers, and sensors
Global Access: Localized experiences for global populations

eCOA Reporting
and Analytics for Real-Time Clinical Trial Oversight.

Most eCOA platforms delay insight until it’s too late to act. YPrime’s eCOA reporting delivers near real-time visibility into participant activity, site performance, and data quality—supporting proactive oversight and faster intervention.

Instant Access: Query millions of records in seconds
Custom Dashboards: Filter by site, subject, visit, form, or timepoint
Compliance Monitoring: Identify risks early with trend analysis and alerts
Audit-Ready Trails: Every entry, update, and correction fully traceable

Want a preview? Book a demo of our eCOA reporting dashboards.

Pre-Validated, Configurable eCOAs for Faster Startup.

Watch our video and discover how YPrime’s eCOA platform helps you solve for certainty, while reducing site and patient burden.

Get Started    

Pre-Validated, Configurable eCOAs for Faster Startup.

Watch our video and discover how YPrime’s eCOA platform helps you solve for certainty, while reducing site and patient burden.

Get Started    

Future-Ready eCOA—Built for What’s Next in Clinical Trials.

47% faster study startup

100+ countries supported

BYOD and provisioned device ready

Accelerate Your Trial Timelines.
Improve Data Capture.

Drive
47% faster

startup times

With pre-validated eCOA libraries.

Ensure
high-quality
data

With built-in validation.

Simplify
user
experience

With our easy-to-use interface.

CASE STUDY

Rapid eCOA Rescue for a
Global Phase 3 Trial.

Smiling young woman holding a smartphone, representing patient engagement and rapid eCOA deployment in a global Phase 3 clinical trial rescue

When a global Phase 3 oncology study faced critical delays due to protocol amendments, a leading sponsor turned to YPrime for a rapid eCOA deployment across 216 sites, 900 patients, and 34 countries.

We delivered:

Our pre-validated eCOA platform ready for immediate deployment
Pre-configured to handle complex study changes with ease
Strategic guidance from our therapeutic area specialists ensured seamless implementation

Results included:

Rapid global rollout using pre-validated eCOA
Seamless implementation of protocol amendments
High-quality, consistent data across all regions
YPrime has a clean and seamless UI. It is able to take the data and put it into graphs and figures to show where the data is trending.
– Head of Real-World Data Analytics, Top 20 Pharma Customer of YPrime eCOA

Trusted eCOA Partner for Global Clinical Trials

YPrime’s eCOA platform has been deployed in nearly 1,000 clinical trials across 100+ countries and 19 therapeutic areas. Sponsors rely on YPrime for studies requiring rapid startup, mid-study adaptation, and inspection-ready data from first patient in through database lock.

Globe icon representing the number of clinical studies implemented globally with YPrime’s technology platform

~1,000

Studies Implemented Globally

Search icon representing the number of therapeutic areas supported by YPrime’s clinical trial solutions

19+

Therapeutic
Areas

Three stars with arrows icon representing YPrime’s years of experience in eClinical technology and services

15+

Years eClinical Technology and Services

Future-Ready eCOA for
Your Clinical Trials.

Clinical research is evolving—and your eCOA platform must keep pace. YPrime’s eCOA is built to support new endpoints, connected devices, evolving regulatory expectations, and global scale—without sacrificing data quality or startup speed. See how YPrime can support your next study.

Explore eCOA Insights from Our Experts.

Gain expert perspectives on clinical trial design, eCOA data quality, operational efficiency, and how sponsors solve with certainty in modern clinical research.

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